
Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.










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Bactrim Product Description
Drug Uses
Bactrim is a synthetic antibacterial combination product to block the metabolism in cells of pathogenic microorganisms. It provides broad-spectrum antibacterial activity against infections caused by Gram-positive and Gram-negative pathogens.
Antimicrobial Bactrim is prescribed for children (aged 2 month old and above) and for adult patients for the treatment of:
middle ear infection
wound and skin infections
urogenital system infections
gastrointestinal tract infections
upper and lower respiratory tract infections
Bactrim dose is titrated individually, taking into account the disease severity and the microorganisms’ sensitivity to antibiotics. In acute infections, the patients are indicated to take Bactrim for 5-7 days. Children over 12 and adults are prescribed to take one Bactrim DS (double strength) tablet in the morning and evening after meals.
A pediatric dose of Bactrim is titrated for children under 12 years of age, considering the child’s body weight and age. Elderly patients with normal renal function are usually indicated with the regular dose for adults.
Missed dose
If you have missed a pill of antibacterial drug Bactrim, take it as soon as you remember and keep complying with the regular dosing schedule. Do not take the missed dose of Bactrim, if it is time for the next dose of synthetic antimicrobial drug. The drug should be taken according to the dosing schedule, do not take extra medicine to make up the missed dose of Bactrim.
More Information
Bactrim should be indicated with caution in patients with asthma and prone to allergic reactions. During antimicrobial treatment with Bactrim, the patients are advised to drink plenty of water and have urine output in order to reduce the possibility of crystalluria.
Bactrim pills are recommended to take whole, after a meal with a full glass of water. To ensure the antibiotic therapy efficiency, the patient should comply with the prescribed dosage regimen and not withdraw Bactrim use at the first signs of the state improvement. Premature withdrawal of the antibiotic therapy may cause the infection relapse.
Storage
Bactrim can be stored for 5 years if kept in the outer carton at temperature not above 25°C. It is recommended to protect antibiotic Bactrim from light.
Bactrim Safety Information
Warnings
Bactrim is advised to be prescribed with extreme caution to elderly patients taking diuretics (particularly, thiazides), because it increases the risk of Werlhof's disease (autoimmune thrombocytopenic purpura).
Clinical studies have verified that Bactrim may change an anticoagulant effect of anticoagulants. Therefore, in case of coadministration of antibacterial drug Bactrim with acenocoumarol or warfarin, activated clotting time is recommended to be adjusted again. It should be mentioned that Bactrim may decrease the effectiveness of tricyclic antidepressants, and weaken the contraceptive effect of birth control pills.
Coadministration of Bactrim with immunosuppressive medications (i.e. mercaptopurine, cyclosporine and azathioprine) may result in blood disorders. Bactrim is to be indicated with caution to patients taking antiviral medications. This combination of drugs increases the risk of acute confusional state and muscle twitching (myoclonus).
Disclaimer
This information on the Bactrim is provided for general informational purposes only and shall not be used as recommendations how to treat bacterial infections if such treatment was not indicated by your doctor.
The online pharmacy shall not be liable for any incidental, indirect, or consequential damage which may arise through the access to information about Bactrim and from the combination antibiotic therapy.
Bactrim Side Effects
Therapeutic action of Bactrim may be accompanied with such undesirable effects as hyperkalemia, headache and candidiasis. Sometimes undesirable effects involve the gastrointestinal system and cause vomiting, appetite loss, diarrhea, or nausea. In addition, different allergic skin reactions can be observed during the treatment with Bactrim.
Most common of allergic undesirable effects include urticaria and rash. Overdose of antibiotic Bactrim may cause such undesirable effect as high serum potassium concentration in the body. Very rarely, Bactrim is reported to cause hypersensitivity. If a severe form of this undesirable effect is met, Bactrim intake should be immediately stopped.
Accutane, which is isotretinoin, - is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.

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Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.

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Fights diarrhea (acute and chronic of various genesis: allergic, emotional, drug, radiation, with a change in diet and quality of food, in violation of metabolism and absorption), used for regulation of stool in patients with ileostomy. Loperamide (the effective ingredient of Imodium) reduces the tone and motility of the smooth muscles of the intestine. Slows down the peristalsis and increases the transit time of intestinal contents. Increases the tone of the anal sphincter, promotes retention of fecal masses and reduced urge to defecate. The effect develops quickly and lasts for 4-6 hours.

Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.

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