Eldepryl - antiparkinsonian agent. The MAO-B selective inhibitor, participating in dopamine metabolism, etc. catecholamines. Dopamine metabolism, the return capture oppresses at the level of presynaptic nerves, promoting thereby increase in its concentration in kernels of extrapyramidal system, etc. parts of a brain.
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Eldepryl Product Description
Drug Uses
Eldepryl is an antiparkinson drug, which inhibits the reuptake of dopamine and enhances its concentration in the brain. Eldepryl is used for treatment of patients with Parkinson's disease. Clinical studies have demonstrated that Eldepryl, used during the early stages of Parkinson's disease, helps patients maintain the working ability and go without levodopa for a longer time.
The combination therapy of Eldepryl with levodopa strengthens and extends the levodopa action. Therefore, the drug is prescribed to those patients, who show poor clinical efficacy to levodopa/carbidopa therapy. The recommended daily dose makes 10 mg of Eldepryl, divided into two doses (5 mg in the morning and 5 mg in the evening).
If Eldepryl is indicated in combination with levodopa, the dose of levodopa is recommended to be reduced by an average of 30% in three days of application. It has been found that the higher doses of Eldepryl do not increase the therapeutic effect, and even may cause the development of side effects.
Missed Dose
If you found out that you had forgotten to take a dose of Eldepryl, take it as soon as possible. If you’ve remembered about the missed dose of the antiparkinsonian agent just before the next dose, skip the missed dose of Eldepryl, do not double the next one and return to a normal scheduled dose.
More Information
Antiparkinson medication Eldepryl is recommended to be taken during a meal (breakfast and dinner). The daily dose of the antiparkinson drug should not be adjusted, if Eldepryl is used in patients with impaired liver and kidney function. Alcoholic beverages are recommended to be avoided during the treatment of Parkinson's disease.
Storage
Eldepryl should be stored at room temperature, not exceeding 25°C in the original package. A container with Eldepryl tablets should be kept tightly closed, away from children and pets.
Eldepryl Safety Information
Warnings
Patients are recommended to adhere to a prescribed dosage regimen and to avoid taking a daily dose exceeding 10mg, since the risk of non-selective inhibition of MAO is increased. Despite that there is no data on Eldepryl impact on the melanoma development in patients with Parkinson's disease, periodic skin examinations are recommended and the recommendations on the antiparkinson drug application should be complied. Clinical studies have demonstrated that Eldepryl in combination with levodopa, may significantly lower the blood pressure in patients with cardiovascular diseases.
Disclaimer
Information about Parkinson's disease, contained in the review of Eldepryl, shall not be considered to substitute for the neurologist’s medical advice. The online pharmacy shall not be responsible for any kind of damage, caused by incorrect use of the information on antiparkinsonian agent Eldepryl.
Eldepryl Side Effects
Usually, Eldepryl is well-tolerated. All undesirable effects, which may be caused by this antiparkinsonian agent, are mild. Most common undesirable effects, which can be met during the therapy with Eldepryl include headache, hallucinations, dizziness, sleeping disorders, nausea, stomatitis and confusion. Some undesirable effects, observed in patients during Eldepryl therapy, may require the antiparkinsonian agent use to be stopped. These undesirable effects include depression, arrhythmia, delusions, syncope, angina pectoris and hypertension.
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