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Persantine
Persantine
Active ingredient: Persantine

The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.

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May
26
airmail
Delivery period
14-21 days
$9.95
Tracking# available in 14 days
ems
Delivery period
14-21 days
$29.95
Tracking# available in 5 days
Availability:In Stock 46 packs
Persantine 100
Package Per pill Total price Save Order
100 x 30 Pills $1.12
$33.54
+ Bonus - 4 Pills
- Add to cart
100 x 60 Pills $0.94
$56.10
+ Bonus - 4 Pills
$10.80 Add to cart
100 x 90 Pills $0.87
$78.67
+ Bonus - 7 Pills
$22.50 Add to cart
100 x 180 Pills $0.81
$146.36
+ Bonus - 11 Pills
$55.80 Add to cart
100 x 270 Pills $0.79
$214.05
+ Bonus - 11 Pills
Free Trackable Delivery
$89.10 Add to cart
100 x 360 Pills $0.78
$281.74
+ Bonus - 11 Pills
Free Trackable Delivery
$122.40 Add to cart
Persantine 25
Package Per pill Total price Save Order
25 x 60 Pills $0.60
$35.82
+ Bonus - 4 Pills
- Add to cart
25 x 90 Pills $0.50
$45.13
+ Bonus - 7 Pills
$9.00 Add to cart
25 x 120 Pills $0.45
$54.45
+ Bonus - 7 Pills
$18.00 Add to cart
25 x 180 Pills $0.41
$73.07
+ Bonus - 11 Pills
$34.20 Add to cart
25 x 270 Pills $0.37
$101.01
+ Bonus - 11 Pills
$62.10 Add to cart
25 x 360 Pills $0.36
$128.95
+ Bonus - 11 Pills
$86.40 Add to cart
Package Example

Your order will be packed safe and secure and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has a size and a look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm) and it does not disclose its contents

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Persantine product description


Persantine belongs to the group of drugs affecting the system of blood and blood formation in the human body. The composition includes Dipyridamole - a medical agent used in order to reduce coagulation. Dipyridamole was originally proposed as a coronary-extending (dilating heart vessels) antianginal (anti-anginal) medical preparation. According to experimental data, the drug expands coronary vessels (heart vessels), increases the volume rate of coronary (cardiac) blood flow, improves the supply of myocardium (cardiac muscle) with oxygen. Increases myocardial tolerance to hypoxia (cardiac muscle resistance to oxygen deficiency).

When the circulation in the main coronary vessels is disturbed, this pharmaceutical promotes an improvement in blood circulation in the collateral vasculature (along the blood vessels, by which blood flows around the affected vessel). Under its influence, the total peripheral resistance (total mechanical resistance to blood flow through the vessels) also decreases, the systemic blood pressure decreases somewhat, and cerebral circulation improves.

In the mechanism of the vasodilator effect of Dipyridamole, an increase in the formation of adenosine, one of the participants in the autoregulation of coronary blood flow (regulation by the heart of the rate of blood flow through its vessels) plays a significant role. Dipyridamole is a competitive inhibitor of adenosine deaminase, an enzyme that cleaves adenosine. As coronary dilatant, Dipyridamole is currently limited in use. It is sometimes used for chronic ischemic heart disease.

An important feature of Dipyridamole is its ability to inhibit aggregation (adhesion) of platelets and prevent the formation of clots (blood clots) in the vessels. The drug stimulates the biosynthesis (formation in the body) of prostacyclin and suppresses the synthesis of thromboxanes (biologically active substances taking part in the regulation of vascular tone and the coagulation system of blood).


Persantine safety information


This medical remedy is contraindicated in patients with the prevalent stenosing atherosclerosis of the coronary arteries (a disease of the heart vessels characterized by a decrease in their lumen), thrombocytopenia, intolerance of components, liver and kidney failure in severe form, hemorrhagic syndrome, arterial hypotension, subaortic stenosis of the aorta, cardiac decompensated insufficiency. It is forbidden to prescribe this medication to patients younger than 12 years.


Persantine side effects


According to anti-aggregation activity, Dipyridamole is inferior to Ticlopidine, close to Acetylsalicylic acid. At the same time, it is better tolerated than Acetylsalicylic acid, does not exert ulcerogenic (causing gastric ulcer) action. Dipyridamole is usually well tolerated. In some cases, short-term reddening of the face (vasodilator effect), increased pulse, allergic skin rash.

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