
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.


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Secnidazole product description
Considered to be a medical remedy of the new generation, the tablets Secnidazole are widely used in medical practice. The effectiveness of the action, the ease of reception, accessibility - these are the reasons for this. It is assigned in cases of the treatment of intestinal infections, giardiasis, bacterial vaginosis, trichomoniasis. Secnidazole successfully fights against those illnesses. Interacting with DNA, it causes disruption of its spiral structure, rupture of threads suppresses the synthesis of nucleic acids and causes the death of bacterial cells and protozoan cells. This medical preparation is bactericidal for most obligate anaerobic bacteria, stops the vital activity of many protozoa, breaking intracellular chemical reduction reactions, which are characteristic only for anaerobic metabolism. The price of Secnidazole is quite acceptable. And in combination with high efficiency, ease of use provides it with a worthy place in a range of similar means. Among the most popular indications to consume Secnidazole, there is a lambliasis common in children. In some cases, along with curing it, there was noted a healing of ulcers and elimination of Helicobacter pylori.
Secnidazole safety information
The medication is to be taken orally, immediately before meals, swallowing it with a small amount of water (or mixing with semi-liquid food). In case of such a diagnosis as Trichomoniasis2 g at once is taken.With amoebiasis of the intestine, giardiasis: adults are prescribed 2 g once, children - 30 mg/kg once (asymptomatic amoebiasis - for 3 days). The remedy is prescribed for the patients with amebiasis of the liver in the following way: adults - 1.5 g per day (once or several times), during 5 days, and children - 30 mg/ kg/day (once or several times), within 5 days. Secnidazole enhances the anticoagulant effect of coumarin derivatives or indanedione. The combination of it with disulfiram causes paranoid reactions and psychoses, with alcohol - symptomatic alcohol-antagonistic reaction (abdominal cramps, nausea, vomiting, headache, the rush of blood to the face). The drug contraindications include hypersensitivity (including other imidazole derivatives), pathological changes in the blood formula (including history), organic CNS diseases inactive form; breastfeeding (at the time of treatment is suspended), pregnancy.
Secnidazole side effects
A single reception is usually enough. It is only necessary to strictly follow the dosage and treatment plan prescribed by the doctor. The use of Secnidazole once allows you to reduce the time of abstinence from sexual activity. This is necessary during treatment. As well as refusal from the use of alcohol. All recommendations should be considered before the start of the treatment procedure. The adverse reactions are manifested in the form of digestive disorders, nausea, pain in the stomach, metallic taste in the mouth, glossitis, stomatitis, mild leukopenia, dizziness, impaired coordination and ataxia, paresthesia, polyneuropathy, urticaria. Those are infrequent and not very pronounced. Therefore, do not require the withdrawal of the drug. According to reviews on Secnidazole, the drug is well tolerated by both adults and children. The preparation is appointed from the age of 12.
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An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.

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Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
