
Most indications for the use of such glucocorticoids as Medrol are due to their anti-inflammatory, immunosuppressive and anti-allergic properties. Due to these properties, the following therapeutic effects are achieved: reduction of the number of immune cells in the vicinity of inflammation; reduction of vasodilation; stabilization of lysosomal membranes; inhibition of phagocytosis; reduction of production of prostaglandins and related compounds.


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Product Description
Synthetic glucocorticosteroid, which has anti-inflammatory, antiallergic and immunosuppressive activity. It has a strong effect on carbohydrate, protein and lipid metabolism. By activity is close to prednisolone, but almost does not have mineralocorticoid (sodium retardation) activity, which provides better tolerability. It is slowly absorbed when administered intramuscularly and has a longer lasting effect than hydrocortisone and prednisolone.
Safety information
Indications and usage
Collagenoses, rheumatism, infectious nonspecific polyarthritis, bronchial asthma, acute lymphoblastic and myeloblastic leukemia, infectious mononucleosis, neurodermatitis, eczema and other skin diseases, various allergic diseases, Addison's disease, acute adrenocortical insufficiency, hemolytic anemia, glomerulonephritis, acute pancreatitis, shock and Collapse in surgical interventions;It is used to suppress the rejection reaction in the gomotransplantation of organs and tissues.
Mode of application
When bronchial asthma is prescribed by mouth, starting at 12-40 mg per day;Maintenance dose - 4-12 mg per day.When chronic polyarthritis (inflammation of several joints) is prescribed, starting from 6-20 mg per day.In rheumatoid arthritis they begin with Dr.eskers 0.8-1.5 mg / kg, then gradually diminish.
Depending on the disease, the daily dose averages 0.004-0.048 grams of methylprednisolone.The appointment of large doses may be required for multiple sclerosis (a systemic disease of the membranes of the nerve cells of the brain and spinal cord) - up to 0.2 g / day, brain edema - 0.2 g / day, organ transplants (transplantation) - up to 0,007 g/day.If the medicine has been used for a long time, its cancellation should be gradual.Doses are selected individually.With long-term treatment (to achieve the effect of the drug with a minimum of side effects), it is possible to take (in the mornings) a day after the dose equal to twice the daily dose.
Contraindications
Systemic fungal and other infections, hypersensitivity to the medicine, pregnancy, lactation, osteoporosis.
Side effects
The delay of sodium and water in the body, loss of potassium, raising blood pressure, muscle weakness, osteoporosis (impaired bone supply, accompanied by an increase in its fragility), damage to the walls of the stomach, reducing the body's resistance to infection, mental disorders, suppression of adrenal function, menstrual cycle disorder.
Accutane, which is isotretinoin, - is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.

Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.

Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!

Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.

Antabuse - the medicine for treatment of alcoholism. The effect of medicine is implemented due to blockade of acetaldehydehydrogenaz which takes part in ethanol metabolism in consequence of which rises the level of acetaldehyde which causes a number of negative symptoms (including hot flashes, hyperemia of face, vomiting, tachycardia and increase in pressure). These effects arising after alcohol intake lead to development of cause-effect relations and rejections of alcohol intake. Thus, the patient has a conditioned-reflex disgust for a smell and taste of alcohol.

Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.

Fights diarrhea (acute and chronic of various genesis: allergic, emotional, drug, radiation, with a change in diet and quality of food, in violation of metabolism and absorption), used for regulation of stool in patients with ileostomy. Loperamide (the effective ingredient of Imodium) reduces the tone and motility of the smooth muscles of the intestine. Slows down the peristalsis and increases the transit time of intestinal contents. Increases the tone of the anal sphincter, promotes retention of fecal masses and reduced urge to defecate. The effect develops quickly and lasts for 4-6 hours.

Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.

Olanzapine is an antipsychotic drug (neuroleptic). It is shown in schizophrenia in adults, psychotic disorders, bipolar affective disorder in adults, depressive states.

Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.

Kamagra Gold - a pharmacological remedy that betters an erectile function. Created by the Indian pharmaceutical enterprise Ajanta Pharma Ltd, is an analog of the outstanding Viagra. This Sildenafil remedy is released in the form of turquoise rhombus tablet. A full name of this generic is Kamagra-100 Gold. Purchasing Kamagra Gold you obtain an expected result and simultaneously win at price.

Femara tablets are a non-steroidal antitumor drug, a specific inhibitor of the aromatase enzyme. The mechanism of action of Femara is based on inhibiting the growth of tumor cells by binding to the subunit of the aromatase enzyme, which takes part in the synthesis of estrogens that stimulate the development of cancer cells. According to the description, the drug is recommended for use in the initial form of breast cancer during the postmenopausal period, as well as for patients with a common type of breast cancer in the postmenopausal period that have been treated with anti-estrogens (Tamoxifen).
