Danazol is used in endometriosis (with concomitant infertility), benign neoplasms of the breast (fibrocystic mastopathy), primary menorrhagia, premenstrual syndrome, primary premature puberty, gynecomastia.
Flagyl - antiprotozoan and antimicrobic drug. It is prescribed at treatment of protozoan inspections (abenteric amebiasis, including amoebic abscess of liver, an intestinal amebiasis, trichomoniasis, giardiasis, balanthidiasis, lambliasis, skin leushmaniosis, mecotic vaginitis, mecotic urethritis), pseudomembranous colitis, gastritises, ulcer, prevention of postoperative complications (especially interventions at segmented intestine, perirectal area, appendectomy, gynecologic operations).
The antifungal agent which has activity against dermatophytes, yeasts, dimorphic fungi and eumycetes. It is also active against staphylococci and streptococci. The therapeutical indications of the drug include: mycoses of the gastrointestinal tract, eyes, genital organs, chronic recurrent vaginal candidiasis, dermatomycosis, onychomycosis, Candida, folliculitis, dermatophytosis, systemic fungal infections (blastomycosis, candidiasis, paracoccidioides, coccidioidomycosis, cryptococcosis, histoplasmosis, hromomikoz, sporotrichosis, paronychia, fungal sepsis, fungal pneumonia); leishmaniasis; tinea versicolor, prevention of fungal infections in patients with a high risk of their development. The mechanism of action is inhibition of fungal membrane ergosterol synthesis and the violation of the cell wall permeability.