Capoten suppresses activity of angiotensin-converting-enzyme therefore angiotensin-I turns into angiotensin II - substance which has strong vasoconstrictive action. Capoten reduces secretion of Aldosteronum in suprarenal cortex, at the same time the delay of sodium and water in an organism decreases. Capoten slows down process of bradykinin destruction and promotes increase of E2 prostaglandin, and also nitrogen oxide that causes vasodilating action. Thanks to these effects it is decreased the increased arterial pressure, the general peripheric resistance decreases, pressure in the right auricle, in a small circle of blood circulation decreases and cordial emission increases.
Diamox weak diuretic which is taken at edematous syndrome, craniocereberal hypertensia, glaucoma, epilepsy and mountain disease. Inhibits carbonic anhydrase in a proximal gyrose tubule of nephron, increases removal with urine Na+, K+, hydrocarbonate, does not influence Cl- egestion, alkalinizes urine.
Furosemide - «Loopback" diuretic; causes quickly coming, severe and short-term diuresis. Has natriuretic and chloro effects, increases clearance of K+, Ca2+, Mg2+. It is taken at edematous syndrome, cirrhosis, diseases of kidneys, heavy course of arterial hypertension and hypercalcemia.
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.