Amaryl - a medicine of group of sulphonylurea, the peroral hypoglycemic medicine. It has an initially prolonged effect. The mechanism of action consists in stimulation of secretion and release of insulin from beta cells of a pancreas (pancreatic effect). It also increases sensitivity of fatty and muscular tissues to effect of insulin (extrapancreatic effect).
An oral hypoglycemic means, which inhibiting the intestinal alpha-glycosidase, reduces the enzymatic conversion of di-, oligo - and polysaccharides to mono-saccharides, thereby reducing the absorption of glucose from the intestine and postprandial hyperglycemia. It is used to treat diabetes, of type 2 under the ineffective diet, the course of which shall not be less than 6 months, type 1diabetes within the combination therapy.
Prednisolone is a synthetic analogue of the adrenal cortex secreted by the hormones cortisone and hydrocortisone. Unlike cortisone and hydrocortisone, prednisolone does not cause a noticeable delay in sodium and water, and only slightly increases the release of potassium. The drug has a pronounced anti-inflammatory, antiallergic, anti exudative, anti-shock, antitoxic effect.