Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Lipitor refers to inhibitors of hydroxymethylglutaryl coenzyme A-reductase. It is used to lower the level of LDL cholesterol (bad cholesterol) in the blood, total cholesterol, triglycerides (another kind of fat) and apolipoprotein B (protein required for cholesterol production). Lipitor is also used to increase the blood cholesterol level of HDL cholesterol (good cholesterol). It is necessary to reduce the risk of hardening of the arteries, which can lead to heart attacks, strokes and peripheral vascular diseases.