Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.

A peripheral vasodilator, blocks postsynaptic alpha1-adrenergic receptors and prevents the vasoconstrictive influence of catecholamines. It reduces pressure in the pulmonary veins and the right atrium significantly, it also reduces pulmonary vascular resistance moderately. The drug therapeutic indications include: arterial hypertension; CHF (in combination therapy), Raynaud's syndrome and disease, pheochromocytoma, peripheral vascular spasm on the background of poisoning with ergot alkaloids. Prostatic hyperplasia